USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: SPTB2_HUMAN USC-OGP 2-DE database:  SPTB2_HUMAN SPTB2_HUMAN General information about the entry View entry in simple text format Entry name SPTB2_HUMAN Primary accession number Q01082 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Spectrin beta chain, non-erythrocytic 1; AltName: Full=Beta-II spectrin; AltName: Full=Fodrin beta chain; AltName: Full=Spectrin, non-erythroid beta chain 1;. Gene name Name=SPTBN1 Synonyms=SPTB2 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1237: pI=4.73; Mw=33231 Cross-references UniProtKB/Swiss-Prot Q01082; SPTB2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name SPTB2_HUMAN Primary accession number Q01082 Secondary accession number(s) B2RP63 O60837 Q16057 Q53R99 Q59ER3 Q8IX99 Sequence was last modified on  October 17, 2006 (version 2) Annotations were last modified on  March 15, 2017 (version 182) Name and origin of the protein Description RecName: Full=Spectrin beta chain, non-erythrocytic 1; AltName: Full=Beta-II spectrin; AltName: Full=Fodrin beta chain; AltName: Full=Spectrin, non-erythroid beta chain 1; Gene name Name=SPTBN1 Synonyms=SPTB2 Encoded on Name=SPTBN1; Synonyms=SPTB2 Keywords 3D-structure; Acetylation; Actin capping; Actin-binding; Alternative splicing; Calmodulin-binding; Cell membrane; Complete proteome; Cytoplasm; Cytoskeleton; Glycoprotein; Membrane; Phosphoprotein; Polymorphism; Reference proteome; Repeat. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M96803; AAA60580.1; -; mRNA EMBL AF327441; AAO15362.1; -; mRNA EMBL AB209748; BAD92985.1; ALT_INIT; mRNA EMBL AC093110; AAY24229.1; -; Genomic_DNA EMBL AC092839; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471053; EAX00147.1; -; Genomic_DNA EMBL BC137282; AAI37283.1; -; mRNA EMBL BC137283; AAI37284.1; -; mRNA EMBL S65762; AAB28324.1; -; mRNA EMBL AJ005694; CAA06678.1; -; mRNA EMBL AJ238723; CAB91088.1; -; Genomic_DNA CCDS CCDS33198.1; -. [Q01082-1]; . CCDS CCDS33199.1; -. [Q01082-3]; . PIR A44159; A44159; . PIR A47213; A47213; . RefSeq NP_003119.2; NM_003128.2. [Q01082-1]; . RefSeq NP_842565.2; NM_178313.2. [Q01082-3]; . RefSeq XP_005264574.1; XM_005264517.2. [Q01082-1]; . RefSeq XP_006712150.1; XM_006712087.2. [Q01082-1]; . RefSeq XP_016860268.1; XM_017004779.1. [Q01082-1]; . RefSeq XP_016860269.1; XM_017004780.1. [Q01082-1]; . RefSeq XP_016860270.1; XM_017004781.1. [Q01082-1]; . UniGene Hs.503178; -; . UniGene Hs.705692; -; . PDB 1AA2; X-ray; 2.00 A; A=173-280 PDB 1BKR; X-ray; 1.10 A; A=172-280 PDB 3EDV; X-ray; 1.95 A; A/B=1697-2015 PDBsum 1AA2; -; . PDBsum 1BKR; -; . PDBsum 3EDV; -; . ProteinModelPortal Q01082; -; . SMR Q01082; -; . BioGrid 112589; 124; . DIP DIP-33182N; -; . IntAct Q01082; 84; . MINT MINT-1136298; -; . STRING 9606.ENSP00000349259; -; . DrugBank DB01373; Calcium; . iPTMnet Q01082; -; . PhosphoSitePlus Q01082; -; . SwissPalm Q01082; -; . BioMuta SPTBN1; -; . DMDM 116242799; -; . EPD Q01082; -; . MaxQB Q01082; -; . PaxDb Q01082; -; . PeptideAtlas Q01082; -; . PRIDE Q01082; -; . Ensembl ENST00000333896; ENSP00000334156; ENSG00000115306. [Q01082-3]; . Ensembl ENST00000356805; ENSP00000349259; ENSG00000115306. [Q01082-1]; . GeneID 6711; -; . KEGG hsa:6711; -; . UCSC uc002rxu.4; human. [Q01082-1]; . CTD 6711; -; . DisGeNET 6711; -; . GeneCards SPTBN1; -; . H-InvDB HIX0002055; -; . HGNC HGNC:11275; SPTBN1; . HPA HPA012685; -; . HPA HPA013149; -; . MIM 182790; gene; . neXtProt NX_Q01082; -; . OpenTargets ENSG00000115306; -; . PharmGKB PA36104; -; . eggNOG KOG0035; Eukaryota; . eggNOG COG5069; LUCA; . GeneTree ENSGT00760000118813; -; . HOVERGEN HBG057912; -; . InParanoid Q01082; -; . KO K06115; -; . PhylomeDB Q01082; -; . TreeFam TF313446; -; . Reactome R-HSA-373753; Nephrin interactions; . Reactome R-HSA-375165; NCAM signaling for neurite out-growth; . Reactome R-HSA-445095; Interaction between L1 and Ankyrins; . Reactome R-HSA-5673001; RAF/MAP kinase cascade; . Reactome R-HSA-6807878; COPI-mediated anterograde transport; . SignaLink Q01082; -; . SIGNOR Q01082; -; . ChiTaRS SPTBN1; human; . EvolutionaryTrace Q01082; -; . GeneWiki SPTBN1; -; . GenomeRNAi 6711; -; . PRO PR:Q01082; -; . Proteomes UP000005640; Chromosome 2; . Bgee ENSG00000115306; -; . CleanEx HS_SPTBN1; -; . ExpressionAtlas Q01082; baseline and differential; . Genevisible Q01082; HS; . GO GO:0030673; C:axolemma; ISS:BHF-UCL; . GO GO:0032437; C:cuticular plate; IEA:Ensembl; . GO GO:0005737; C:cytoplasm; IDA:HGNC; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0031430; C:M band; IEA:UniProtKB-SubCell; . GO GO:0005730; C:nucleolus; IDA:HGNC; . GO GO:0014069; C:postsynaptic density; IEA:Ensembl; . GO GO:0043234; C:protein complex; IEA:Ensembl; . GO GO:0008091; C:spectrin; TAS:ProtInc; . GO GO:0014731; C:spectrin-associated cytoskeleton; NAS:BHF-UCL; . GO GO:0003779; F:actin binding; TAS:ProtInc; . GO GO:0030506; F:ankyrin binding; IPI:BHF-UCL; . GO GO:0045296; F:cadherin binding; IDA:BHF-UCL; . GO GO:0051020; F:GTPase binding; IPI:UniProtKB; . GO GO:0005543; F:phospholipid binding; IEA:InterPro; . GO GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; TAS:Reactome; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0005200; F:structural constituent of cytoskeleton; IMP:BHF-UCL; . GO GO:0051693; P:actin filament capping; IEA:UniProtKB-KW; . GO GO:0007411; P:axon guidance; TAS:Reactome; . GO GO:0007182; P:common-partner SMAD protein phosphorylation; IEA:Ensembl; . GO GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:Reactome; . GO GO:0043001; P:Golgi to plasma membrane protein transport; IMP:BHF-UCL; . GO GO:0000165; P:MAPK cascade; TAS:Reactome; . GO GO:0071709; P:membrane assembly; IMP:BHF-UCL; . GO GO:0000281; P:mitotic cytokinesis; IMP:BHF-UCL; . GO GO:0007009; P:plasma membrane organization; IMP:BHF-UCL; . GO GO:1900042; P:positive regulation of interleukin-2 secretion; IMP:UniProtKB; . GO GO:1903078; P:positive regulation of protein localization to plasma membrane; IMP:UniProtKB; . GO GO:0072661; P:protein targeting to plasma membrane; IMP:BHF-UCL; . GO GO:1903076; P:regulation of protein localization to plasma membrane; IGI:UniProtKB; . GO GO:0007184; P:SMAD protein import into nucleus; IEA:Ensembl; . CDD cd00014; CH; 2; . Gene3D 1.10.418.10; -; 2; . Gene3D 2.30.29.30; -; 1; . InterPro IPR001589; Actinin_actin-bd_CS; . InterPro IPR001715; CH-domain; . InterPro IPR011993; PH_dom-like; . InterPro IPR001605; PH_dom-spectrin-type; . InterPro IPR001849; PH_domain; . InterPro IPR018159; Spectrin/alpha-actinin; . InterPro IPR016343; Spectrin_bsu; . InterPro IPR002017; Spectrin_repeat; . Pfam PF00307; CH; 2; . Pfam PF00435; Spectrin; 17; . PIRSF PIRSF002297; Spectrin_beta_subunit; 1; . PRINTS PR00683; SPECTRINPH; . SMART SM00033; CH; 2; . SMART SM00233; PH; 1; . SMART SM00150; SPEC; 17; . SUPFAM SSF47576; SSF47576; 1; . SUPFAM SSF50729; SSF50729; 1; . PROSITE PS00019; ACTININ_1; 1; . PROSITE PS00020; ACTININ_2; 1; . PROSITE PS50021; CH; 2; . PROSITE PS50003; PH_DOMAIN; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

[Home]